If you arrive by TRAIN: exit the Central train station through the main exit towards city center: turn left (eastwards) , pass through the tram platform and walk on for about 10 minutes (follow the signs to NEMO). Pass by the DoubleTree hotel and Bibliotheek and cross the bridge towards the NEMO (green shiplike building). Turn right to Pier no.5. Hotelboat Amsterdam is the second ship on the lefthand side.
When travelling by CAR: follow the A10 east to exit no. S114, follow the signs CENTRUM, after the tunnel take a right turn. You follow this street 'Piet Heinkade' until the first possible left turn. Follow the Kattenburgerstraat and straight ahead on the Prins Hendrikkade. Across the IJ-tunnel you go straight ahead on the crossing but take the first right to turn to enter Oosterdok. Look for Pier no.5.
Parking on the street is expensive, check for beter options www.bereikbaar.amsterdam.nl, look for P+R
If you use a navigation system or Googlemaps search Oosterdok 28, 1011VZ